That the new signal signaling pathways that targeted cancer treatment

UCLA's Jonsson Comprehensive Cancer new signal pathway has been identified by researchers of the Center is linked to cell growth and development. The activities of the newly discovered route contribution may formation as such common cancer Lymphoma, leukemia.

136 Believed gene blockage results damage to route is increased cell division spur cancer starts. It is important for cell division of the cells will be to speed up this blockage. Dr. Michael Teitell UCLA Description: "this route without problems happen, cancer can be".

Highlight the new understanding of cell growth of these findings will influence how damaged DNA. Previously it only three DNA damage response results impossible that was believed. Contains the results of these three.

interrupted to allow damage repairedDamaged cell to cell growth, go into hibernation to eliminate off replication changes after DNADamaged cells die

Studies indicate, however, results of the fourth it's now possible: called by the damaged cells on mature too soon spur. 136 Is associated with the new signal pathway genes to block this does not. As a result, cell proliferation of immature cells quick is natural endpoint mature not allowed. Finally, leads this Lymphoma or leukemia.

The fact that the results of this fourth environmental factors, such as asbestos only cause DNA damage is not clarified. It is recommended you may too much exposure to Sun and toxic chemicals known DNA damage in the past, while the natural physiological processes leads to the same result, UCLA survey results.

Could reopen this route in order to reverse the negative effects after researchers began their drug development: Study also recommended that current oral diabetes drugs (metformin) treatment benefits. Is effective to activate a route of previous research efforts, metformin problem suggests. Some research shows that patients take metformin low instance Lymphoma, leukemia.

To start the signal path additional research Teitell and his team to understand the processes associated with cancer plan. Because of the provided research funds national sanitation and leukemia and Lymphoma Society